The CLEANEST: Supplement Brands (Our Top Truly Toxin-Free Picks!)

True wellness starts from within—but navigating the world of “clean” supplements can be confusing. Many so-called healthy options still contain synthetic additives, fillers, or hidden toxins that do more harm than good! That’s where we come in. We’ve done the research—so you can skip the label decoding & go straight to the cleanest, safest brands!

Choosing truly clean, whole-food, organic supplements isn’t just about feeling good—it’s about supporting your long-term health at the deepest level. At Keeping It Real Clean, we hold the highest standards, ditching even “better” ingredients that don’t make the cut & sharing only the absolute SAFEST & BEST! (Learn more here).

Below, discover our favorite toxin-free supplement brands, carefully vetted for their quality, purity, performance, & integrity. Plus, snag exclusive promo codes to make your switch even easier! 

top 7 Cleanest  supplement Brands:

1. Poofy organics 🌿Best For: Ultra-pure supplements

Poofy Organics isn't just clean-it's next level pure. As the #goldstandard in USDA Certified Organic supplements & personal care, they offer 500+ meticulously crafted high-performance products, all held to the strictest toxin-free standards. Poofy is the real deal with ultra-potent, effective formulations! (Learn more here.)

  • ❤️Currently Loving: Poofy Organics Vitamin D3

          Sunshine in a bottle—plant-based D3 for strong bones & stellar immunity! #Glow

    Bestseller: Poofy Organics Revive Multi Collagen Protein Powder

           Rebuild, glow, & thrive—this multi-collagen powder is your daily dose of love! #YASS

    🔥Rave Review: Poofy Organics Super shrooms mushroom tincture

          "This tincture is a must-have for us. Great energy, boosting our immune system,

    fabulous antioxidant properties. We won't be without it. Love that Poofy Organics

    cares enough to make this!! They truly talk the talk & walk the walk!"

    ➡️ Get 10% off your first order w/code: KEEPINGITREALCLEAN

2. Purium 🌿Best For: Organic superfood-powered nutrition

Purium is the #goldstandard in USDA Certified Organic superfood supplements. Their vegan-powered, ultra-pure blends are designed to supercharge your body & elevate your wellness. To level up from the inside out, flood your body with Purium's potent, health-boosting nutrients for true #lifechanging transformation! (Learn more here.)

  • ❤️Currently Loving: Purium Aqua Vibrance

           Revolutionizing hydration w/the purest oxygenated HO for #insta-worthy skin!

    Best Seller: Purium Anti-Aging Dark Berry Protein

           This ultra-nourishing vegan protein shake is the #fountainofyouth & oh-so delicious!

    🔥Rave Review: Purium Ultimate Lifestyle transformation (best Cleanse & reset!)

          "ULT transformed my life! Within the first week, my skin rash cleared! By the end of

    the first 30 days, I released 10 pounds of inflammation & I no longer have intense

    pain in my intestines regularly. This program is a game-changer for me! I feel better

    than I have in years! Highly recommend this program to anyone & everyone!"

    ➡️ Get $50+ off first order w/code: KEEPINGITREALCLEAN

    (PLUS 15%+ off ALL future orders—forever!)

3. nature's Brands 🌿Best For: budget-friendly Supplements

Nature’s Brands delivers pure USDA Certified Organic personal care & supplements that prioritize your health—& your wallet. Infused with raw whole food nutrition, minerals, antioxidants & herbs, their uber-clean, potent formulas prove that affordable supplements can be truly toxin-free! Ultimate clean, ultimate health! (Learn more here.)

➡️ Note: Limited selection.

4. Earthley 🌿Best For: Herbal-powered wellness supplements

Earthley champions whole, nourishing ingredients with radical transparency. Known for their herbal tinctures & high-quality, affordable supplements, they prioritize toxin-free solutions that truly work. A fan-favorite among clean living enthusiasts, Earthley delivers plant-based goodness with proven power! (Learn more here.)

  • ❤️Currently Loving: Earthley Cod liver oil

          Power up your day with brain-boosting, skin-loving cod liver oil. #GlowGirl

    Best Seller: Earthley nourish her naturally

           This nourishing herbal blend supports women like only nature can! #NatureKnows

    🔥Rave Review: Earthley Turmeric & Black Pepper

          "I woke up with a terrible headache & I was just about to reach for my Tylenol when I

    remembered I had the turmeric/black pepper capsules. I took 2 & within 5 minutes

    no more headache! I am so impressed with this one that it needed to be shared!"

    ➡️Get 10% off first order w/code: KEEPINGITREALCLEAN

    ➡️ Note: Limited selection.

5. Mary Ruth’s 🌿Best For: clean, plant-based supplements

Mary Ruth’s Organics is redefining wellness with ultra-clean, vegan, USDA Certified Organic supplements that fuel your body from the inside out. With a relentless focus on purity, their wellness formulas deliver only the best. The ultimate health hack—no wonder they keep going viral! (Learn more here.)

  • ❤️Currently Loving: Mary Ruth's Probiotic Beauty Capsules

           This powerful probiotic blend boosts collagen, hydrates, & fortifies your hair!

    Best Seller: Mary Ruth's Liquid Multivitamin

          The ultimate liquid-form multivitamin to level-up your energy, wellness & hair health!

    🔥Rave Review: Mary Ruth's Hair, Skin, & Nails Gummies

          "These are amazing. Postpartum did me dirty this time, I lost SO much hair. I started

    taking these & have so much new healthy growth. I have bangs without even getting

    bangs lol! They also taste really great. Highly recommend!"

6. dr. Mercola 🌿Best For: physician-formulated

Dr. Mercola elevates clean supplements with USDA Certified Organic, plant-powered formulas designed to restore & revitalize. By sourcing the world’s finest ingredients with premium quality standards, they ensure maximum potency—delivering deep healing & health. Pure perfection! (Learn more here.)

  • ❤️Currently Loving: Dr. Mercola Methyl B12 Energy Boost

    Focus, fuel, & feel-good vibes—spray your way to better days! #CleanEnergy

    Best Seller: dr. mercola antarctic krill oil

            Fuel your brain, heart, and glow—Krill Oil’s got the goods! #OmegaUp

    🔥Rave Review: dr. mercola Liposomal Vitamin C

    "I started taking this Vitamin C after getting disappointed in another one. And this

    one works way better! Have been taking it for 3 months & haven't gotten any cold.

    My immune system seems to be stronger than ever!"

7. Pique 🌿Best For: Radiant skin + next-gen wellness

Pique fuses ancient wisdom with cutting-edge science to deliver powerhouse supplements that actually work. Their patented Cold Extraction Technology + Triple Toxin Screening = ultra-pure, high-impact nutrients your body absorbs. Glowing skin, strong immunity, & beauty from within? Yes please!:) (Learn more here.)

 🔄Ready To Make the Switch?

Switching to clean, toxin-free supplements isn’t just a wellness upgrade—it’s a powerful step toward lasting health & vitality! When you fuel your body with the purest ingredients, you're not only supporting your daily energy, focus & immunity—you're investing in your long-term well-being. (Also check: Our Cleanest Natural Remedies Recommendations!)

Your choices matter. Let’s keep it real clean, one supplement at a time!✨

>>> Thanks for using the links provided! We may earn a small commission at no additional cost to you <<<